Support method development in :
- ORF optimization and sequence, RE analysis
- Optimization of mRNA secondary structure
- Choice of promoter, Optimize promoter transcription start and Kozak, choice of plasmid, selection marker, and host
- Optimize pcd (picogram/cell/day) and volumetric productivity
- Optimize recombinant induction protocol at lab and pilot scale
- Media optimization
- Clone stability
- Clone purity